I am a Professor of Biostatistics and Epidemiology at the London School of Hygiene & Tropical Medicine. My interests encompass various research areas in epidemiology and public health evaluation, from methodology, applied research, and software implementation. My methodological work focuses on the development of study designs and statistical methods, applied in particular to time series methods, quasi-experimental studies, and survival analysis. I have contributed to the development and extensions of a number of statistical techniques, such as distributed lag models, smoothing methods and meta-analytical models. My substantive research covers several of areas, from investigations of the health effects of environmental or occupational factors to evaluation of public health interventions. I am a strong advocate of open science and reproducible research, and have contributed with the implementation of statistical methods in freely-available software and with release of code in public repositories.